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The integration of adverse outcome pathways and aggregate exposure pathways for food safety testing: pesticides as a case study
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The integration of adverse outcome pathways and aggregate exposure pathways for food safety testing: pesticides as a case studyChemical risk assessment is moving towards non animal approaches that rely on the mechanistic understanding of toxicity. In this respect, the adverse outcome pathway (AOP) framework is a promising tool to capture chemical agnostic mechanistic understanding of toxicological processes. AOPs link a molecular initiating event to a specific adverse outcome via a series of key events and key event relationships. Sharing common key features to the AOP
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Psychoanalysts have traditionally been expert at uncovering what afflicts and damages people
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with updated references and suggested readings
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This chapter presents an overview of the current understanding of mycotoxin contamination of cocoa
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